publications
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| + | ====== Research Publications ====== | ||
| + | ^ # ^ Authors | ||
| + | |~~=row()~~.| Wigler, M.H. and Weinstein, I.B. | 1975 | A preparative method for obtaining enucleated mammalian cells. Biochemical and Biophysical Research Commun. 63 : 669-674. PMID: 1169063 | {{: | ||
| + | |~~=row()~~.| Wigler, M.H., Ford, J.P. and Weinstein, I.B. | 1975 | Glucocorticoid inhibition of fibrinolytic activity production by tumor cells. | ||
| + | |~~=row()~~.| Wigler, M.H. and Weinstein, I.B. | 1976 | A tumor promoter induces plasminogen activator. Nature 259: 232-233. PMID: 1250353 | {{: | ||
| + | |~~=row()~~.| Wigler, M.H. and Axel, R. | 1976 | Nucleosomes in metaphase chromosomes. Nucleic Acids Res. 3: 1463-1472. PMC343005| {{: | ||
| + | |~~=row()~~.| Wigler, M.H., Silverstein, | ||
| + | |~~=row()~~.| Weinstein, I.B. and Wigler, M. | 1977 | Cell culture studies provide new information on tumour promoters. Nature 270: 659-690. | {{: | ||
| + | |~~=row()~~.| Pellicer, A., Wigler, M., Axel, R. and Silverstin, S. | 1978 | The transfer and stable integration of the HSV thymidine kinase gene into mouse cells. Cell 14: 133-141. PMID: 208776 | {{: | ||
| + | |~~=row()~~.| Wigler, M., DeFeo, D. and Weinstien, I.B. | 1978 | Induction of plasminogen activator in cultured cells by macrocyclic plant diterpene esters and other agents related to tumor promotion. Cancer Res. 38: 1434-1437. PMID: 639070 | {{: | ||
| + | |~~=row()~~.| Wigler, M., Pellicer, A., Silverstein, | ||
| + | |~~=row()~~.| Wigler, M., Pellicer, A., Silverstein, | ||
| + | |~~=row()~~.| Wigler, M., Sweet, R., Sim, G.K., Wold, B., Pellicer, A., Lacy, E., Maniatis, T., Silverstein, | ||
| + | |~~=row()~~.| Wold, B., Wigler, M., Lacy, E., Maniatis, T., Silverstein, | ||
| + | |~~=row()~~.| Wigler, M., Perucho, M., Kurtz, D., Dana, S., Pellicer, A., Axel, R. and Silverstein, | ||
| + | |~~=row()~~.| Perucho, M., Hanahan, D., Lipsich, L. and Wigler, M. | 1980 | Isolation of the chicken thymidine kinase gene by plasmid rescue. Nature 285: 207. PMID: 6246445 | {{: | ||
| + | |~~=row()~~.| Perucho, M., Hanahan, D. and Wigler, M. | 1980 | Genetic and physical linkage of exogenous sequences in transformed cells. Cell 22: 309-317. PMID: 6253083 | {{: | ||
| + | |~~=row()~~.| Hanahan, D., Lane, D., Lipsich, L., Wigler, M. and Botchan, M. | 1980 | Characteristics of an SV40-plasmid recombinant and its movement into and out of the genome of a murine cell. Cell 21: 127-139. PMID: 6250708 | {{: | ||
| + | |~~=row()~~.| Perucho, M. and Wigler, M. | 1981 | Linkage and expression of foreign DNA in cultured animal cells. Cold Spring Harbor Symp. Quant. Biol., 45: 829-838. PMID: 6942952 | {{: | ||
| + | |~~=row()~~.| Wigler, M., Levy, D. and Perucho, M. | 1981 | The somatic replication of DNA methylation. Cell 24: 33-40. PMID: 6263490 | {{: | ||
| + | |~~=row()~~.| Wigler, M.H. | 1981 | The inheritance of methylation patterns in vertebrates. | ||
| + | |~~=row()~~.| Perucho, M., Goldfarb, M., Shimizu, K., Lama, C., Fogh, J. and Wigler, M. | 1981 | Human-tumor-derived cell lines contain common and different transforming genes. Cell 27: 467-476. PMID: 6101201 | {{: | ||
| + | |~~=row()~~.| Goldfarb, M., Shimizu, K., Perucho, M. and Wigler, M. | 1982 | Isolation and preliminary characterization of a human transforming gene from T24 bladder carcinoma cells. Nature 296: 404-409. PMID: 7063039 | {{: | ||
| + | |~~=row()~~.| Taparowsky, E., Suard, Y., Fasano, O., Shimizu, K., Goldfarb, M., Wigler, M. | 1982 | Activation of the T24 bladder carcinoma transforming gene is linked to a single amino acid change. Nature, 300: 762-765. PMID: 7177195 | {{: | ||
| + | |~~=row()~~.| Shimizu, K., Goldfarb, M., Perucho, M. Wigler, M., | 1983 | Isolation and preliminary characterization of the transforming gene of a human neuroblastoma cell line. Proc. Natl. Acad. Sci., USA, 80: 383-387. PMID: 6300838 | {{: | ||
| + | |~~=row()~~.| Shimizu, K., Goldfarb, M., Suard, Y., Perucho, M., Li, Y., Kamata, T., Feramisco, J., Stavnezer, E., Fogh, J. and Wigler, M. | 1983 | Three human transforming genes are related to the viral ras oncogenes. Proc. Natl. Acad. Sci., USA 80: 2112-2116. PMID: 6300838 | {{: | ||
| + | |~~=row()~~.| Fasano, O., Taparowsky, E., Fiddes, J., Wigler, M. and Goldfarb, M. | 1983 | Sequence and structure of the coding regions of the human H- ras -1 gene from T24 bladder carcinoma cells. | ||
| + | |~~=row()~~.| Kwoh, T.J., Zipser, D. and Wigler, M. | 1983 | Mutational analysis of the cloned chicken thymidine kinase gene. J. Mol. Appl. Genetics, 2: 191-200. PMID: 6875426 | {{: | ||
| + | |~~=row()~~.| Barker, D., McCoy, M., Weinberg, R., Goldfarb, M., Wigler, M., Burt, R., Gardner, E. and White, R. | 1983 | A test of the role of two oncogenes in an inherited predisposition to colon cancer. | ||
| + | |~~=row()~~.| Taparowsky, E., Shimizu, K., Goldfarb M., and Wigler M., | 1983 | Structure and activation of the N- ras gene. Cell, 34: 581-586. PMID: 6616621 | {{: | ||
| + | |~~=row()~~.| Shimizu, K., Birnbaum, D., Ruley, M.A., Fasano, O., Suard, Y, Edlund, L., Taparowsky, E., Goldfarb, M. and Wigler, M. | 1983 | The structure of the Ki- ras gene of the human lung carcinoma cell line Calu-1. | ||
| + | |~~=row()~~.| Ryan, J., Barker, P.E., Shimizu, K., Wigler, M., and Ruddle, F.H. | 1983 | Chromosomal assignment of a family of human oncogenes. Proc. Natl. Acad. Sci., USA 80: 4460-4463. PMID: 6576347 | {{: | ||
| + | |~~=row()~~.| Powers, S., Kataoka, T., Fasano, O., Goldfarb, M., Strathern, J., Broach, J., and Wigler, M. | 1984 | Genes in Saccharomyces cerevisiae encoding proteins with domains homologous to the mammalian ras proteins. Cell, 36: 607-612. PMID: 6365329 | {{: | ||
| + | |~~=row()~~.| Fasano, O., Aldrich, T., Tamanoi, F., Taparowsky, E., Furth, M., and Wigler, M. | 1984 | Analysis of the transforming potential of the human H- ras genes by random mutagenesis. Proc. Natl. Acad. Sci., 81: 4008-4012. PMID: 6308118 | {{: | ||
| + | |~~=row()~~.| Kataoka, T., Powers, S., McGill, C., Fasano, O., Strathern, J., Broach, J. and Wigler, M. | 1984 | Genetic analysis of yeast RAS1 and RAS2 genes. Cell, 37: 437-445. PMID: 6327067 | {{: | ||
| + | |~~=row()~~.| Fasano, O., Birnbaum, D., Edlund, L., Fogh, J. and Wigler, M. | 1984 | New human transforming genes detected by a tumorigenicity assay. Molecular and Cellular Biology, 4 : 1695-1705. PMID: 6092933 | {{: | ||
| + | |~~=row()~~.| Tamanoi, F., Walsh, M., Kataoka, T. and Wigler, M. | 1984 | A product of yeast RAS2 gene is a guanine nucleotide binding protein. Proc. Natl. Acad. Sci. USA 81: 6924-6928. PMID: 6438624 | {{: | ||
| + | |~~=row()~~.| Kataoka, T., Powers, S., Cameron, S., Fasano, O., Goldfarb, M., Broach, J., and Wigler, M. | 1985 | Functional homology of mammalian and yeast RAS genes. Cell, 40: 19-26. PMID: 2981628 | {{: | ||
| + | |~~=row()~~.| Toda, T., Uno, I., Ishikawa, T., Powers, S., Kataoka, T., Broek, D., Cameron, S., Broach, J., Matsumoto, K., and Wigler, M. | 1985 | In yeast, RAS proteins are controlling elements of the adenylate cyclase. Cell, 40: 27-36. PMID: 2981630 | {{: | ||
| + | |~~=row()~~.| Gross, M., Sweet, R., Sathe, G., Yokoyama, S., Fasano, O., Goldfarb, M., Wigler, M., Rosenberg, M. | 1985 | Purification and characterization of human H- RAS proteins produced in E . coli . Molecular Cellular Biology, 5: 1015-1024. PMID: 3923330 | {{: | ||
| + | |~~=row()~~.| Broek, D., Samily, N., Fasano, O., Fujiyama, A., Tamanoi, F., Northup, J., and Wigler, M. | 1985 | Differential activation of yeast adenylate cyclase by wild type and mutant RAS proteins. Cell, 41: 763-769. PMID: 3891097 | {{: | ||
| + | |~~=row()~~.| Kataoka, T., Broek, D. and Wigler, M | 1985 | DNA sequence and characterization of the S . cerevisiae gene encoding adenylate cyclase. Cell, 43 : 493-505. PMID: 2934138 | {{: | ||
| + | |~~=row()~~.| Birchmeier, C., Broek, D. and Wigler, M. | 1985 | RAS proteins can induce meiosis in Xenopus oocytes. Cell, 43: 615-621. PMID: 2416466 | {{: | ||
| + | |~~=row()~~.| Birchmeier, C., Broek, D., Toda, T., Powers, S., Kataoka T. and Wigler, M. | 1985 | Conservation and divergence of RAS protein function during evolution. Cold Spring Harbor Symposium on Quantative Biology, Volume L, pp. 721-725. PMID: 3007012 | {{: | ||
| + | |~~=row()~~.| Young, D., Waitches, G., Birchmeier, C., Fasano, O. and Wigler, M. | 1986 | Isolation and characterization of a new cellular oncogene encoding a protein with multiple potential transmembrane domains. Cell, 45: 711-719. PMID: 3708691 | {{: | ||
| + | |~~=row()~~.| Birchmeier, C., Birnbaum, D., Waitches, G., Fasano, O. and Wigler, M. | 1986 | Characterization of an activated human ros gene. Molecular Cellular Biology, 6: 3109-3116. PMID: 3785223 | {{: | ||
| + | |~~=row()~~.| Powers, S., Michaelis, S., Broek D., Anna-A., S.S., Field, J., Herskowitz, I. and Wigler, M. | 1986 | RAM , a gene of yeast required for a functional modification of RAS proteins and for production of mating pheromone a -factor. Cell, 47: 413-422. PMID: 3533274 | {{: | ||
| + | |~~=row()~~.| Sass, P., Field, J., Nikawa, J., Toda, T. and Wigler, M. | 1986 | Cloning and characterization of the high affinity cAMP phosphodiesterase of S . cerevisiae . Proc. Natl. Acad. Sci., 83: 9303-9307. PMID: 3025832 | {{: | ||
| + | |~~=row()~~.| Birchmeier, C., Young, D. and Wigler, M. | 1986 | Characterization of two new human oncogenes. | ||
| + | |~~=row()~~.| Broek, D., Toda, T., Michaeli, T., Levin, L., Birchmeier, C., Zoller, M., Powers, S. and Wigler, M. | 1987 | The S . cerevisiae CDC25 gene product regulates the RAS /adenylate cyclase pathway. Cell, 48: 789-799. PMID: 3545497 | {{: | ||
| + | |~~=row()~~.| Toda, T., Cameron, S., Sass, P., Zoller, M., Scott, J.D., McMullen, B., Murwitz, M., Krebs, E.G. and Wigler, M. | 1987 | Cloning and characterization of BCY1 , a locus encoding a regulatory subunit of the cyclic AMP dependent protein kinase in Saccharomyces cerevisiae. Molecular Cellular Biology, 7: 1371-1377. PMID: 3037314 | {{: | ||
| + | |~~=row()~~.| Field, J., Broek, D., Kataoka, T., and Wigler, M. | 1987 | Guanine nucleotide activation of, and competition between, RAS proteins from Saccharomyces cerevisiae. Molecular Cellular Biology, 7: 2128-2133. PMID: 3299060 | {{: | ||
| + | |~~=row()~~.| Rabin, M., Birnbaum, D., Young, D., Birchmeier, C., Wigler, M. and Ruddle, F. | 1987 | Human ROS1 and MAS1 oncogenes are located in regions of chromosome 6 associated with tumor-specific rearrangements. | ||
| + | |~~=row()~~.| Johnson, K.E., Cameron, S., Toda, T., Wigler, M. and Zoller, M. | 1987 | Expression in Escherichia coli of BCY1 , the regulatory subunit of cyclic AMP-dependent protein kinase from Saccharomyces cerevisiae . J. Biological Chemistry 262: 8636-8642. PMID: 3036817 | {{: | ||
| + | |~~=row()~~.| Toda, T., Cameron, S., Sass, P., M. Zoller and Wigler, M. | 1987 | Three different genes in Saccharomyces cerevisiae encode the catalytic subunits of the cAMP dependent protein kinase. Cell, 50: 277-287. PMID: 3036373 | {{: | ||
| + | |~~=row()~~.| Birchmeier, C., Sharma, S. and Wigler, M. | 1987 | Expression and rearrangement of the ros1 gene in human glioblastoma cells. Proc. Natl. Acad. Sci., 84: 9270-9274. PMID: 2827175 | {{: | ||
| + | ||~~=row()~~.| Nikawa, J., Sass, P. and Wigler, M. | 1987 | Cloning and characterization of the low affinity cyclic AMP phosphodiestrase gene of S. cerevisiae . Molecular and Cellular Biology, 7: 3629-3636. PMID: 2824992 | {{: | ||
| + | |~~=row()~~.| Nikawa, J., Cameron, S., Toda, T., Ferguson, K.M., and Wigler, M. | 1987 | Rigorous feedback control of cAMP levels in S. cerevisiae . Genes and Development, | ||
| + | |~~=row()~~.| Toda, T., Broek, D., Field, J., Michaeli, T., Cameron, S., Nikawa, J., Sass, P., Birchmeier, C., Powers, S. and Wigler, M. | 1987 | Exploring the function of RAS oncogenes by studying the yeast Saccharomyces cerevisiae. Oncogene and Cancer, S.A. Aaronson et al., (eds). Japan Sci. Soc. Press, Tokyo/VNU Sci. Press, pp. 253-260. PMID: 3290050 | {{: | ||
| + | |~~=row()~~.| Levin, L.R., Kuret, J., Johnson, K.E., Powers, S., Cameron, S., Michaeli, M., Wigler, M. and Zoller, M. | 1988 | A mutation in the catalytic subunit of the cAMP-dependent protein kinase that disrupts regulation. Science, 240: 68-70. PMID: 2832943 | {{: | ||
| + | |~~=row()~~.| Cameron, S., Levin, L., Zoller, M. and Wigler, M. | 1988 | cAMP-Independent control of sporulation, | ||
| + | |~~=row()~~.| Toda, T., Cameron, S., Sass, P and Wigler, M. | 1988 | SCH9 , a gene of S. cerevisiae that encodes a protein distinct from, but functionally and structurally related to, cAMP dependent protein kinase catalytic Subunits . Genes and Development, | ||
| + | |~~=row()~~.| Field, J., Nikawa, J., Broek, D., MacDonald, B., Rodgers, L., Wilson, I.A., Lerner, R.A. and Wigler, M. | 1988 | Purification of a RAS -responsive adenylyl cyclase complex from Saccharomyces cerevisiae by use of an epitope addition method. Molecular and Cellular Biology, 8: 2159-2165. PMID: 2455217 | {{: | ||
| + | |~~=row()~~.| Young, D., O' | ||
| + | |~~=row()~~.| Wigler, M., Field, J., Powers, S., Broek, D., Toda, T., Cameron, S., Nikawa, J., Michaeli, T., Colicelli, J., and Ferguson, K. | 1988 | Studies of RAS function in the yeast S. Cerevisiae . Cold Spring Harbor Symposium, vol. LIII, pages 649-655. PMID: 3076094 | {{: | ||
| + | |~~=row()~~.| Powers, S., O' | ||
| + | |~~=row()~~.| Colicelli, J., Birchmeier, C., Michaeli, T., O' | ||
| + | |~~=row()~~.| Sharma, S., Birchmeier, C., Nikawa, J., O' | ||
| + | |~~=row()~~.| Michaeli, T., Field, J., Ballester, R., O' | ||
| + | |~~=row()~~.| Ballester, R., Michaeli, T., Ferguson, K., Xu, H-P., McCormick, F. and Wigler, M. | 1989 | Genetic analysis of mammalian GAP expressed in yeast. Cell 59: 681-686. PMID: 2684416 | {{: | ||
| + | |~~=row()~~.| Young, D., Riggs, M., Field, J., Vojtek, A., Broek, D., and Wigler, M. | 1989 | The adenylyl cyclase gene from schizosaccharomyces pombe. Proc. Natl. Acad. Sci., 86: 7989-7993. | {{: | ||
| + | |~~=row()~~.| Field, J. Xu, H-P, Michaeli, T., Ballester, R., Sass, P., Wigler, M., Colicelli, J. | 1990 | Mutations of the adenylyl Cyclase gene that block RAS function in Saccharomyces Cerevisiae. Science, 247: 464-467. PMID: 2405488 | {{: | ||
| + | |~~=row()~~.| Field, J., Vojtek, A., Ballester, R., Bolger, G., Colicelli, J., Ferguson, K., Gerst, J., Kataoka, T., Michaeli, T., Powers, S., Riggs, M., Rodgers, L., Wieland, I., Wheland, B. and Wigler, M. | 1990 | Cloning and characterization of CAP , the Saccharomyces cerevisiae gene encoding the 70 kDa adenylyl cyclase associated protein. Cell, 61 : 319-327. | {{: | ||
| + | |~~=row()~~.| Weiland, I., Bolger, G., Asouline, G. and Wigler, M. | 1990 | A method for difference cloning: Gene amplification following subtractive hybridization. Proc. Natl. Acad. Sci., 87 : 2720-2724. PMID: 2138783 | {{: | ||
| + | |~~=row()~~.| Colicelli, J., Field, J., Ballester, R., Chester, N., Young, D., and Wigler, M. | 1990 | Mutational mapping of RAS-responsive domains of the Saccharomyces cerevisiae adenylyl cyclase. Mol. Cell. Biol., 10: 2539-2543. PMID: 2111437 | {{: | ||
| + | |~~=row()~~.| Birchmeier, C., O' | ||
| + | |~~=row()~~.| Wigler, M. | 1990 | GAPs in understanding Ras. Nature, 346: 696-7. PMID: 2201920 | {{: | ||
| + | |~~=row()~~.| Xu, H.-P., Riggs, M., Rodgers, L., and Wigler, M. | 1990 | A gene from S. pombe with homology to E. coli RNAse III blocks conjugation and sporulation when overexpressed in wild type cells. Nucl. Acid Res. 18: 5304. PMID: 2205842 | {{: | ||
| + | |~~=row()~~.| Xu, H-P., Wang, Y., Riggs, M., Rodgers, L. and Wigler, M. | 1990 | Biological activity of the mammalian RAP genes in Yeast. Cell Regulation, 1: 763-769. PMID: 1983087 | {{: | ||
| + | |~~=row()~~.| Ballester, R., Marchuk, D., Boguski, M., Saulino, A., Letcher, R., Wigler, M. and Collins, F. | 1990 | The NF1 locus encodes a protein functionally related to mammalian GAP and yeast IRA proteins. | ||
| + | |~~=row()~~.| Gerst, J., Ferguson, K., Vojtek, A., Wigler, M. and Field, J. | 1991 | CAP: A bifunctional component of the S. cerevisiae adenylyl cyclase complex. Mol. Cell. Biol., 11: 1248-1257. PMID: 1996090 | {{: | ||
| + | |~~=row()~~.| Kawamukai, M., Ferguson, K., Wigler, M. and Young, D. | 1991 | Genetic and biochemical analysis of the adenylyl cyclase of Schizosaccharomyces pombe. Cell Regulation, 2: 155-164. PMID: 1863602 | {{: | ||
| + | |~~=row()~~.| Colicelli, J., Birchmeier, C., Rodgers, L., Riggs, M. and Wigler, M. | 1991 | Expression of three mammalian cDNAs which interfere with RAS function in S. cerevisiae. Proc. Natl. Acad. Sci. USA, 88: 2913-2917. PMID: 1849280 | {{: | ||
| + | |~~=row()~~.| Young, D., O' | ||
| + | |~~=row()~~.| Wang, Y., Xu, H.-P., Riggs, M., Rodgers, L. and Wigler, M. | 1991 | Byr2 , an S. pombe gene encoding a protein kinase capable of partial phenotypic suppression of ras1 - strains. Mol. Cell. Biol., 11: 3554-3563. PMID: 1883874 | {{: | ||
| + | |~~=row()~~.| Wang, Y., Boguski, M., Riggs, M., Rodgers, L. and Wigler, M. | 1991 | Sar1, a gene from Schizosaccharomyces pombe encoding a protein that regulates ras1. Cell Regulation, 2: 453-465. PMID: 2046669 | {{: | ||
| + | |~~=row()~~.| Daar, I., Nebreda, A.R., Yew, N., Sass, P., Paules, R., Santos, E., Wigler, M. and Vande Woude, G.F. | 1991 | The ras oncoprotein and M-phase activity. Science, 253: 74-76. PMID: 1829549 | {{: | ||
| + | |~~=row()~~.| Vojtek, A., Haarer, B., Field, J., Gerst, J., Pollard, T.D., Brown, S. and Wigler, M. | 1991 | Evidence for a functional link between profilin and CAP in the yeast Saccharomyces cerevisiae . Cell, 66: 497-505. PMID: 1868547 | {{: | ||
| + | |~~=row()~~.| Xu, H.-P., Jung V., Riggs M., Rodgers L. and Wigler M. | 1992 | A gene encoding a protein with seven zinc finger domains which acts on the sexual differentiation pathways of Schizosaccharomyces pombe. | ||
| + | |~~=row()~~.| Gerst, J., Rodgers L., Riggs M. and Wigler M. | 1992 | SNC1, a yeast homolog of the synaptic vesicle-associated membrane protein/ | ||
| + | |~~=row()~~.|Kawamukai, | ||
| + | |~~=row()~~.| Shibuya, E.K., Polverino, A.J., Chang, E., Wigler, M. and Ruderman, J.V. | 1992 | Oncogenic Ras triggers the activation of 42-kDa mitogen-activated protein kinase in extracts of quiescent Xenopus oocytes. Proc. Natl. Acad. Sci. USA, 89: 9831-9835. PMID: 1384061 | {{: | ||
| + | |~~=row()~~.| Andersen, L.B., Ballester, R., Marchuk, D.A. Chang, E., Gutmann, D.H., Saulino, A.M., Camonis, J., Wigler, M. and Collins, F.S. | 1993 | A conserved alternative splice in the von Recklinghausen neurofibromatosis ( NF1 ) gene produces two neurofibromin isoforms, both with GAP activity. Mol. Cell. Biol. 13: 487-495. PMID: 8437860 | {{: | ||
| + | |~~=row()~~.| Gutmann, D.H., Boguski, M., Marchuk, D., Wigler, M., Collins, F.S. and Ballester, R. | 1993 | Analysis of the neurofibromatosis type 1 (NF1) GAP-related domain by site-directed mutagenesis. | ||
| + | |~~=row()~~.| Michaeli, T., Bloom, T., Martins, T., Loughney, K., Ferguson, K., Riggs, M., Rodgers, L., Beavo, J., and Wigler, M. | 1993 | Isolation and characterization of a previously undetected human cAMP phosphodiesterase by complementation of cAMP phosphodiesterase deficient S. cerevisiae . J. Biological Chemistry, 268 : 12925-12932. PMID: 8438152 | {{: | ||
| + | |~~=row()~~.| Neiman, A.M., Stevenson, B.J., Xu, H-P., Sprague, G.F. Jr., Herskowitz, I., Wigler, M., and Marcus, S. | 1993 | Functional homology of protein kinases required for sexual differentiation in Schizosaccharomyces pombe and Saccharomyces cerevisiae suggests a conserved signal transduction module in eukaryotic organisms. Mol. Biol. of the Cell 4: 107-120. PMID: 8443406 | {{: | ||
| + | |~~=row()~~.| Lisitsyn, N., Lisitsyn, N. and Wigler, M. | 1993 | Cloning the differences between two complex genomes. Science 259: 946-951. PMID: 8438152 | {{: | ||
| + | |~~=row()~~.| Van Aelst, L., Barr, M., Marcus, S., Polverino, A. and Wigler, M. | 1993 | Complex formation between RAS and RAF and other protein kinases. Proc. Natl. Acad. Sci. USA, 90 : 6213-6217. PMID: 8327501 | {{: | ||
| + | |~~=row()~~.| Chardin, P., Camonis, J.H., Gale, N.W., Van Aelst, L., Schlessinger, | ||
| + | |~~=row()~~.| Bolger, G., Michaeli, T., Martins, T., St. John, T., Steiner, B., Rodgers, L., Riggs, M., Wigler, M. and Ferguson, K. | 1993 | A family of human phosphodiesterases homologous to the Dunce learning and memory gene of Drosophila melanogaster are potential targets for anti-depressant drugs. Molecular and Cellular Biology, 13: 6558-6571. PMID: 8413254 | {{: | ||
| + | |~~=row()~~.| Ohlmeyer, M.H.J., Swanson, M.N., Dillard, L.W., Reader, J.C., Asouline, G., Kobayashi, R., Wigler, M., Still, W.C. | 1993 | Complex synthetic chemical libraries indexed with molecular tags. Proc. Natl. Acad. Sci. USA, 90: 10922-10926. PMID: 7504286 | {{: | ||
| + | |~~=row()~~.| Lisitsyn, N.A., Segre, J.A., Kusumi, K., Lisitsyn, N.M., Nadeau, J.H., Frankel, W.N., Wigler, M. and Landers, E.S. | 1994 | Direct isolation of polymorphic markers linked to a trait by genetically directed representational difference analysis. Nature Genetics, 6: 57-63. PMID: 8136836 | {{: | ||
| + | |~~=row()~~.| Xu, Hao-Peng, White, M., Marcus, S. and Wigler, M. | 1994 | Concerted action of RAS and G proteins in the sexual response pathways of Schizosaccharomyces pombe . Molecular and Cellular Biology, 14: 50-58. PMID: 8264618 | {{: | ||
| + | |~~=row()~~.| Jung, V., Wei, W., Ballester, R., Camonis, J., Mi, S., Van Aelst, L., Wigler, M. and Broek, D. | 1994 | Two types of ras mutants that dominantly interfere with activators of RAS. Mol. Cell. Biol. 14: 3707-3718. PMID: 8196614 | {{: | ||
| + | |~~=row()~~.| Marcus, S., Barr, M., Polverino, A., and Wigler, M. | 1994 | Complexes between STE5 and components of the yeast pheromone-responsive MAP kinase module. | ||
| + | |~~=row()~~.| Chang, E., Barr, M., Wang, Y., Jung, V., Xu, H.-P., and Wigler, M. | 1994 | Cooperative interaction of S. pombe proteins required for mating and morphogenesis. Cell, 79: 131-141. PMID: 7923372 | {{: | ||
| + | |~~=row()~~.| Lisitsyn, N.A., Lisitsina, N.M., Dalbagni, G., Barker, P., Sanches, C.A. Gnarra, J., Linehan, W.M. Reid, B.J. and Wigler, M. | 1995 | Comparative genomic analysis of tumors: detection of DNA losses and amplification. Proc. Natl. Acad. Sci. USA, 92: 151-155. PMID: 7816807 | {{: | ||
| + | |~~=row()~~.| White, M., Nicolette, C., Minden, A., Polverino, A., Van Aelst, L., Karin, M. and Wigler, M. | 1995 | Multiple RAS functions can contribute to mammalian cell transformation. Cell, 80: 533-541. PMID: 7867061 | {{: | ||
| + | |~~=row()~~.| Jung, V., Chen, Li, Hofmann, S.L., Wigler, M., Powers, S. | 1995 | Mutations in the SHR5 gene of Saccharomyces cerevisiae suppress Ras function and block attachment and palmitoylation of Ras proteins. Mol. Cel. Biol. 15: 1333-1342. PMID: 7532279 | {{: | ||
| + | |~~=row()~~.| Van Aelst, L., White, M. and Wigler, M. | 1994 | Ras partners. | ||
| + | |~~=row()~~.| Lisitsyn, N.A., Leach, F.S., Vogelstein, B. and Wigler, M. | 1995 | Detection of genetic loss in tumors by representational difference analysis. Cold Spring Harbor Symposium on Quantative Biology, Volume 59: pp. 585-587. PMID: 7587116 | {{: | ||
| + | |~~=row()~~.| Marcus, S., Polverino, A., Chang, E., Robbins, D., Cobb, M.H., Wigler, M. | 1995 | Shk1, a homolog of the Saccharomyces cerevisiae Ste20 and mammalian p65PAK protein kinases, is a component of a Ras/Cdc42 signaling module in the fission yeast, Schizosaccharomyces pombe . Proc. Natl. Acad. Sci. USA, 92: 6180-6184. PMID: 7597098 | {{: | ||
| + | |~~=row()~~.| Joneson, T., White, M.A., Wigler, M.H. and Bar-Sagi, D. | 1996 | Stimulation of membrane ruffling and MAP kinase activation by distinct effectors of RAS. Science 271: 810-812. PMID: 8628998 | {{: | ||
| + | |~~=row()~~.| Thiagalingam, | ||
| + | |~~=row()~~.| Khosravi-Far, | ||
| + | |~~=row()~~.| Barr, M.M., Tu, H., Van Aelst, L., Wigler, M. | 1996 | Identification of Ste4 as a potential regulator of Byr2 in the sexual response pathway of Schizosaccharomyces pombe. Mol. Cell. Biol. 16: 5597-5603. PMID: 8816472 | {{: | ||
| + | |~~=row()~~.| White, M.A., Vale, T., Camonis, J.H., Schaefer, E., Wigler, M.H. | 1996 | A role for the Ral guanine nucleotide dissociation stimulator in mediating Ras-induced transformation. | ||
| + | |~~=row()~~.| Xu, H.-P., Yanak, B.L., Wigler, M.H., and Gorin, M.B. | 1996 | New polymorphic markers in the vicinity of the pearl locus on mouse Chromosome 13. Mammalian Genome, 7: 16-19. | {{: | ||
| + | |~~=row()~~.| Li, J., Yen, C., Liaw, D., Podsypanina, | ||
| + | |~~=row()~~.| Myers, M.P., Stolarov, J.P., Eng, C., Li, J., Wang, S.I., Wigler, M., Parsons, R. and Tonks, N.K. | 1997 | P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase. | ||
| + | |~~=row()~~.| Tu, H., Barr, M., Dong, D.L. and Wigler, M. | 1997 | Multiple regulatory domains on the Byr2 protein kinase. Mol. Cell. Biol., 17: 5876-5887. PMID: 9315645 | {{: | ||
| + | |~~=row()~~.| Hamaguchi, M., O' | ||
| + | |~~=row()~~.| Lucito, R., Nakamura, M., West, J.A., Han, Y., Chin, K., Jensen, K., McCombie, R., Gray, J.W., and Wigler, M. | 1998 | Genetic analysis using genomic representations. Proc.Natl.Acad.Sci.USA 95: 4487-4492. PMCID:22516 | {{: | ||
| + | |~~=row()~~.| Webb, C.P., Van Aelst, L., Wigler, M.H. and Vande Woude, G.F. | 1998 | Signaling pathways in Ras-mediated tumorigenicity and metastasis. Proc. Natl. Acad. Sci. USA 95: 8773-8778. PMCID: PMC21152 | {{: | ||
| + | |~~=row()~~.| Myers, M., Pass, I., Batty, I.H., Van der Kaay, J., Stolarov, J.P., Hemmings, B.A., Wigler, M.H., Downes, C.P., Tonks, N.K. | 1998 |The lipid phosphatase activity of PTEN is critical for its tumor suppressor function. Proc. Natl. Acad. Sci. USA, 95: 13513-13518. PMCID: PMC24850 | {{: | ||
| + | |~~=row()~~.| Tu, H. and Wigler, M. | 1999 | Genetic evidence for Pak1 autoinhibition and its release by Cdc42. Mol. Cell. Biol., 19: 602-611. PMID: 9858584 | {{: | ||
| + | |~~=row()~~.| Dong, D.L., Liu, R., Sherlock, R., Wigler, M., Nestler, P.H. | 1999 | Molecular forceps from combinatorial libraries prevent the farnesylation of Ras by binding to its carboxy-terminus. Chem. & Biol., 6: 133-141. PMID: 10074468 | {{: | ||
| + | |~~=row()~~.| Lucito, R., West, J., Reiner, A., Alexander, J., Esposito, D., Mishra, B., Powers, S., Norton, L., and Wigler, M. | 2000 | Detecting gene copy number fluctuations in tumor cells by microarray analyis of genomic representations. | ||
| + | |~~=row()~~.| Wen, S., Stolarov, J., Myers, M.P., Su, J.D., Wigler, M.H., Tonks, N.K., and Durden, D.L. | 2001 | PTEN controls tumor-induced angiogenesis. Proc. Natl. Acad. Sci. USA, 98: 4622-4627. PMCID: PMC31884 | {{: | ||
| + | |~~=row()~~.| Casey, W., Mishra, B. and Wigler, M. | 2001 | Placing probes along the genome using pairwise distance data. Algorithms in Bioinformatics, | ||
| + | |~~=row()~~.| Stolarov, J., Chang, K., Reiner, A., Rodgers, L., Hannon, G.J., Wigler, M. and Mittal, V. | 2001 | Design of a retroviral-mediated ecdysone inducible system an its application to the expression profiling of the PTEN tumor suppressor. Proc. Natl. Acad. Sci., 98: 13043-13048. PMCID: 60821 | {{: | ||
| + | |~~=row()~~.| Scheffzek, K., Grünewald, P., Wohlgemuth, S., Kabsch, W., Tu, H., Wigler, M., Wittinghofer, | ||
| + | |~~=row()~~.| Wigler, M. and Mishra, B. | 2002 | Wild by Nature. Science, 296: 1408-1408. PMID: 12029116 | {{: | ||
| + | |~~=row()~~.| Hamaguchi, M., Meth, J.L., von Klitzing, C. Wei, W., Esposito, D., Rodgers, L. Walsh, T., Welch, P., King, M-C. and Wigler, M.H. | 2002 | DBC2, a candidate for a tumor suppressor gene involved in breast cancer Proc. Natl. Acad. Sci., USA 99: 13647-13652. PMCID: PMC129730 | {{: | ||
| + | |~~=row()~~.| Mu, D., Chen, L., Zhang, X., See, L-H., Koch, C.M., Yen, C., Tong, J.J., Spiegel, L., Nguyen, K.C.Q., Servoss, A., Peng, Y., Pei, L., Marks, J.R., Lowe, S., Hoey, T., Jan, L.Y., McCombie, W.R., Wigler, M.H., Powers, S. | 2003 | Genomic amplification and oncogenic properties of the KCNK9 potassium channel gene. Cancer Cell, 3: 297-302. PMID: 12676587 | {{: | ||
| + | |~~=row()~~.| Lucito, R., Healy, J., Alexander, J., Reiner, A., Esposito, D., Chi, M., Rodgers, L., Brady, A., Sebat, J., Troge, J., West, J., Rostan, S., Nguyen, K.C.Q., Powers, S., Ye, K.Q., Olshen, A., Venkatraman, | ||
| + | |~~=row()~~.| Healy, J., Thomas, E., Schwartz, J.T. and Wigler, M. | 2003 | Annotating large genomes with exact word matches. Genome Research 13: 2306-2315. PMCID: PMC403711 | {{: | ||
| + | |~~=row()~~.| Thomas, E.E., Srebro, N., Sebat, J., Navin, N., Healy, J., Mishra, B., and Wigler, M. | 2004 | Distribution of short, paired duplications in mammalian genomes. Proc. Natl. Acad. Sci., USA, 101: 10349-10354. PMCID: PMC478600 | {{: | ||
| + | |~~=row()~~.| Sebat, J., Muthuswamy, L., Troge, J., Alexander, J., Young, J., Lundin, P., Maner, S., Massa, H., Walker, M., Chi, M., Navin, N., Lucito, R., Healy, J., Hicks, J., Ye, K., Reiner, A., Gilliam, T.C., Trask, B., Patterson, N., Zetterberg, A., Wigler, M. | 2004 | Large-Scale Copy Number Polymorphism in the Human Genome. Science, 305: 525-528. PMID: 15273396 | {{: | ||
| + | |~~=row()~~.| Olshen, A., Venkatraman, | ||
| + | |~~=row()~~.| Daruwala, R.-S, Rudra, A., Ostrer, H., Lucito, R., Wigler, M. and Mishra, B. | 2004 | A versatile statistical analysis algorithm to detect genome copy number variation. Proc. Natl. Acad. Sci., 101: 16292-16297. PMCID: 528962 | {{: | ||
| + | |~~=row()~~.| Jobanputra, V., Sebat, J., Chung, W., Anyane-Yeboa, | ||
| + | |~~=row()~~.| West, J., Healy, J., Casey, W., Mishra, B., and Wigler, M. | 2006 | Validation of S. Pombe Sequence Assembly by Micro-Array Hybridization. Journal of Computational Biology 13: 1-20. PMID: 16740623 | {{: | ||
| + | |~~=row()~~.| Lakshmi, B., Hall, I.M., Egan, C., Alexander, J., Leotta, A., Healy, J., Zender, L., Spector, M., Xue, W., Lowe, S.W., Wigler, M. and Lucito, R. | 2006 | Mouse genomic Representational Oligonucleotide Microarray Analysis: detection of copy number variations in normal and tumor. Proc. Natl. Acad. Sci. USA 103: 11234-11239. PMCID: 1544071 | {{: | ||
| + | |~~=row()~~.| Navin, N., Grubor, V., Hicks, J., Leibu, E., Thomas, E., Troge, J., Riggs, M., Lundin, P., Maner, lS., Sebat, J., Zetterberg, A. and Wigler, M. | 2006 | Prober: Oligonucleotide FISH probe design software. Bioinformatics, | ||
| + | |~~=row()~~.| Zender, L., Spector, M.S., Xue, W., Flemming, P., Cardon-Cardo, | ||
| + | |~~=row()~~.| Hicks, J., Krasnitz, | ||
| + | |~~=row()~~.| Pelham, R.J., Rodgers, L., Hall, I., Lucito, R., Nquyen, K.C.Q., Navin, N., Hicks, J., Mu, D., Powers, S., Wigler, M. and Botstein, M. | 2006 | Identification of alterations in DNA copy number in host stromal cells during tumor progression. Proc. Natl. Acad. Sci. USA 103: 19848-19853. PMCID: 1698871 | {{: | ||
| + | |~~=row()~~.| Sebat, J., Lakshmi, B., Malhotra, D., Lese-Martin, | ||
| + | |~~=row()~~.| Zhao, X., Leotta, A., Qiu, S., Kustanovich, | ||
| + | |~~=row()~~.| Egan, C.M., Sridhar, S., Wigler, M., Hall, I.M. | 2007 | Recurrent DNA copy number variation in the laboratory mouse. Nat. Genet., 39: 1384-1389. PMID: 17965714 | {{: | ||
| + | |~~=row()~~.| Lucito, R., Suresh, S., Walter, K., Pandey, A., B. Lakshmi, Krasnitz, A., Sebat, J., Wigler, M., Klein, A.P., Brune, K., Palmisano, E., Maitra, A., Goggins, M., and Hruban, R.H. | 2007 | Copy-Number Variants in Patients with a Strong Family History of Pancreatic Cancer. Cancer Biol Ther. 6(10) 1592-9. PMCID: 17912030 | {{: | ||
| + | |~~=row()~~.| Alarcon, M., Abrahams, B.S., Stone, J.L., Duvall, J.A., Perederiy, J.V., Bomar,J.M., Sebat, J., Wigler, M., Martin, C.L., Ledbetter, D.H., Nelson, S.F., Cantor, R.M., Geschwind, D.H. | 2008 | Linkage, association, | ||
| + | |~~=row()~~.| Xue, W., Krasnitz, A., Lucito, R., Sordella, R., VanAelst, L., Cordon-Cardo, | ||
| + | |~~=row()~~.| Grubor, V., Krasnitz, A., Troge, J.E., Meth,J.L., Lakshmi, B., Kendall, J.T., Yamrom, B., Alex, G., Pai, D., Navin, N., Hufnagel, L.A., Lee, Y-H., Cook, K., Allen, S., Rai, K.R., Damle, R.N., Calissano, C., Chiorazzi, N., Wigler, M. and Esposito, D. | 2008 | Novel genomic alterations and clonal evolution in Chronic Lymphosytic Leukemia revealed by Representational Oligonucleotide Microarray Analysis (ROMA). Blood, 113: 1294-1303. PMCID: 18922857 | {{: | ||
| + | |~~=row()~~.| Zender, L., Xue, W., Zuber, J., Semighini, C.P., Krasnitz, A., Ma, B., Zender, P., Kubicka, S., Luk, J.M., Schirmacher, | ||
| + | |~~=row()~~.| Hodges, E., Smith, A.D., Kendall, J., Xuan, Z., Ravi, K., Rooks, M., Zhang, M.Q., Ye, K., Bhattacharjee, | ||
| + | |~~=row()~~.| Bric A, Miething C, Bialucha CU, Scuoppo C, Zender L, Krasnitz A, Xuan Z, Zuber J, Wigler M, Hicks J, McCombie RW, Hemann MT, Hannon GJ, Powers S, Lowe SW. | 2009 | Functional Identification of tumor-suppressor genes through an in vivo RNA interference screen in a muse lymphoma mode. Cancer Cell. 16:324-35. PMCID: 2829755 | {{: | ||
| + | |~~=row()~~.| Navin, N., Krasnitz, A., Rodgers, R., Cook, K., Meth, J., Kendall, J., Riggs, M., Eberling, Y., Troge, J., Grubor, V., Levy, D., Lundin, P., Månér, S., Zetterberg, A., Hicks, J. and Wigler, M. | 2010 | Inferring tumor progression from genomic heterogeneity. Genome Research, 20: 68-80. PMCID: 2798832. | {{: | ||
| + | |~~=row()~~.| Russnes, H.G., Moen Vollan, H.K., Lingjærde, O.C., Krasnitz, A., Lundin, P., Naume, B., Sørlie, T., Borgen, E., Rye., I.H., Langerød, A., Chin, S-F., Teschendorff, | ||
| + | |~~=row()~~.| Kamalakaran, | ||
| + | |~~=row()~~.| Navin, N., Kendall, J., Troge, J., Andrews, P., Rodgers, L., McIndoo, J., Cook, K., Stepansky, A., Levy, D., Esposito, D., Muthuswamy, L., Krasnitz, A., McCombie, R., Hicks, J., Wigler, M. | 2011 | Tumor evolution inferred by single cell sequencing. Nature, 472: 90-94. PMCID: 21399628 | {{: | ||
| + | |~~=row()~~.| Horev, G., Ellegood, J., Lerch, J.P., Son, Y.E., Muthuswamy, L., Vogel, H., Krieger, A.M., Buja, A., Henkelman, R.M., Wigler, M., Mills, A.A. | 2011 | Dosage-dependent phenotypes in models of 16p11.2 lesions found in autism. Proc. Natl. Acad. Sci., USA, 108: 17076-17081. PMCID: 3193230 | {{: | ||
| + | |~~=row()~~.| Levy, D., Ronemus, M., Yamrom, B., Lee, Y-H., Leotta, A., Kendall, J., Marks, S., Lakshmi, B., Pai, D., Ye, K., Buja, A., Krieger, A., Yoon, S., Troge, J., Rodgers, L., Iossifov, I., Wigler, M. | 2011 | Rare de novo and transmitted copy-number variation in autistic spectrum disorders. Neuron, 70: 886-897. PMCID: 21658582 | {{: | ||
| + | |~~=row()~~.| Gilman, S.R., Iossifov, I., Levy, D., Ronemus, M., Wigler, M., and Vitkup, D. | 2011 | Rare de novo variants associated with autism implicate a large functional network of genes involved in formation and function of synapses. Neuron 70, 898-907. PMCID: 3607702 | {{: | ||
| + | |~~=row()~~.| Lee, Y-H., Ronemus, M., Kendall, J., Lakshmi, B., Leotta, A., Levy, D., Esposito, D., Grubor, V., Ye, K., Wigler, M., and Yamrom, B. | 2012 | Reducing system noise in copy number data using principal components of self-self hybridizations. Proc. Natl. Acad. Sci., USA, 109: E103-E110. PMCID: 3271883 | {{: | ||
| + | |~~=row()~~.| Baslan, T., Kendall, K., Rodgers, L., Cox, H., Riggs, R., Stepansky, A., Troge, J., Kandasamy, R., Esposito, D., B. Lakshmi, Wigler, M., Navin, N., and Hicks, J. | 2012 | Genome wide copy number analysis of single cells. Nature Protocols, 7: 1024-1041. PMCID: 5069701 | ||
| + | |~~=row()~~.| Iossifov, I., Ronemus, M., Levy, D., Wang, Z., Hakker, I., Rosenbaum, J., Yamrom, B., Lee, Y-H., Narzisi, G., Leotta, A., Kendall, J., Grabowska, E., Ma, B., Marks, S., Rodgers, L., Stepansky, A., Troge, J., Andrews, Bekritsky, M., Pradhan, K., Ghiban, E., Kramer, M., Parla, J., Demeter, R., Fulton, L., Fulton, R.S., Magrini, V.J., Ye, K., Darnell, J.C., Darnell, R.B., Mardis, E.R., Wilson, R.K., Schatz, M.C., McCombie, W.R., Wigler, M. | 2012 | De novo gene disruptions in children on the autistic spectrum. Neuron, 74: 285-299. PMCID: 3619976 | {{: | ||
| + | |~~=row()~~.| Xue, W., Kitzing, T., Roessler, S., Zuber, J., Krasnitz, A., Schultz, N., Revill, K., Weissmueller, | ||
| + | |~~=row()~~.| Stadler, Z.K., Esposito, D., Shan, S., Vijai, J., Yamrom, B., Levy, D., Lee, Y-H., Kendallo, J., Leotta, A., Ronemus, M., Hansen, N., Sarrel, K., | ||
| + | |~~=row()~~.| Wigler, M. | 2012 | Broad applications of single-cell nucleic acid analysis in biomedical research. Genome Medicine 2012, 4:79. PMCID: 3580448 | ||
| + | |~~=row()~~.| Krasnitz, A., Sun, G., Andrews, P., Wigler, M. | 2013 | Target inference from collections of genomic intervals. | ||
| + | |~~=row()~~.| Donnenberg, A.D., Hicks, J.B., Wigler, M., and Donnenberg, V.S. | 2013 | The cancer stem cell: Cell type or cell state? Cytometry, A 83, 5-7. PMCID: | ||
| + | |~~=row()~~.| Shi, J. Whyte, W.A., Zepeda-Mendoza, | ||
| + | |~~=row()~~.| Ronemus, M., Iossifov, I., Levy, D. Wigler, M. | 2014 | The role of de novo mutation in the genetics of autism spectrum disorders. Nature Reviews Genetics, 15: 133-141. | {{: | ||
| + | |~~=row()~~.| Warburton, D., Ronemus, M., Kline, J., Jobanputra, V., Williams, I., Anyane-Yeboa, | ||
| + | |~~=row()~~.| Dago, A.E., Stepansky, A., Carlsson, A., Luttgen, M., Kendall, J., Baslan, T., Kolatkar, A., Wigler, M., Bethel, K., Gross, M.E., Hicks, J., Kuhn, P. | 2014 | Rapid Phenotypic and Genomic Change in Response to Therapeutic Pressure in Prostate Cancer Inferred by High Content Analysis of Single Circulating Tumor Cells. | ||
| + | |~~=row()~~.|Narzisi, | ||
| + | |~~=row()~~.| Levy, D. and Wigler, M. | 2014 | Facilitated Sequence Counting and Assembly by Template Mutagenesis. Proc. Natl. Acad. Sci., USA, 111: E4632-4637. | ||
| + | |~~=row()~~.| Iossifov, I., O' | ||
| + | |~~=row()~~.| Rye, I.H., Ludin, P., Maner, S., Fjellda, R., Naume, B., Wigler, M., Hicks, J., Borresen-Dale, | ||
| + | |~~=row()~~.| Jayaprakash, | ||
| + | |~~=row()~~.| Baslan, T., Kendall, J., Ward, B., Cox, H., Leotta, A., Rodgers, L., Riggs, M., D’Italia, S., Sun, G., Yong, M., Miskimen, K., Gilmore, H., Dimitrova, N., Krasnitz, A., Harris, L., Wigler, M., Hicks, J. | 2015 | Optimizing sparse sequencing of single cells for highly multiplex copy number profiling. | ||
| + | |~~=row()~~.| Garvin, T., Aboukhalil, R., Kendall, J., Baslan, T., Atwal, G.S., Hicks, J., Wigler, M., Schatz, M.C. | 2015 | Interactive analysis and quality assessment of single-cell copy-number variations. | ||
| + | |~~=row()~~.| Mukhopadhyay, | ||
| + | |~~=row()~~.| Iossifov, I., Levy, D., Allen, J., Ye, K., Ronemus, M., Lee, Y-H., Yamrom, B., Wigler, M. | 2015 | Low load for disruptive mutations in autism genes and their biased transmission. | ||
| + | |~~=row()~~.| Baslan, T., Kendall, J., Rodgers, L., Cox, H., Riggs, M., Stepansky, A., Troge, J., Ravi, K., Esposito, D., Lakshmi, B., Wigler, M., Navin, N., Hicks J. | 2016 | Corrigendum: | ||
| + | |~~=row()~~.| Wang, Z., Andrews, P., Kendall, J., Ma, B., Hakker, I., Rodgers, L., Ronemus, M., Wigler, M. and Levy, D. | 2016 | SMASH, a fragmentation and sequencing method for genomic copy number analysis. | ||
| + | |~~=row()~~.| Andrews, P.A., Iossifov, I., Kendall, J., Marks, S., Muthuswamy, L., Wang, Z., Levy, D. and Wigler, M. | 2016 | MUMdex: MUM-based structural variation detection. | ||
| + | |~~=row()~~.| Fang, H., Bergmann, E., Arora, K., Vacic, V., Zody, M., Iossifov, I., O' | ||
| + | |~~=row()~~.| Ye, K., Iossifov, I., Levy, D., Buja, A., Krieger, A., and Wigler M. | 2017 | Measuring shared variants in cohorts of discordant siblings with applications to autism. | ||
| + | |~~=row()~~.| Krasnitz, A., Kendall, J., Alexander, J., Levy, D., and Wigler, M. | 2017 | Early detection of cancer in blood using single-cell analysis: A proposal. | ||
| + | |~~=row()~~.| Alexander, J., Kendall, J., McIndoo, J., Rodgers, L., Aboukhalil, R., Levy, D., Stepansky, A., Sun, G., Riggs, M., Cox, H., Hakker, I., Nowak, D., Laze, J., Lukani, E., Srivastava, A., Gruschow, S., Yadav, S., Robinson, B., Atwal, G., Trotman, L., Lepor, H., Hicks, J., Wigler, M. and Krasnitz, A. | 2017 | Utility of single cell genomic evaluation of prostate cancer. | ||
| + | |~~=row()~~.| Buja, A., Volfovsky, N., Krieger, A., Lord, C., Lash, A.E., Wigler, M., and Iossifov, I. | 2017 | Damaging de novo mutations diminish motor skills in children on the autism spectrum. | ||
| + | |~~=row()~~.| Buja, A., Volfovsky, N., Krieger, A., Lord, C., Lash, A.E., Wigler, M., and Iossifov, I. | 2017 | Damaging mutations are associated with diminished motor skills and IQ in children on the autism spectrum. bioRxiv/ | ||
| + | |~~=row()~~.| Munoz, A., Yamrom, B., Lee, Y-h., Marks, S., Lin, K-T., Wang, Z., Krainer, A.R., Darnell, R.B., Wigler, M. and Iossifov, I. | 2017 | //De novo// indels within introns comtribute to ASD incidence. | ||
| + | |~~=row()~~.| Kumar, V., Rosembaum, J., Wang, Z., Forcier, T., Ronemus, M., Wigler, M. and Levy, D. | 2018 | Partial bisulfite conversion for unique template sequencing. | ||
| + | |~~=row()~~.| Li, S., Kendall, J., Park, S., Wang, Z., Alexander, J., Moffitt, A., Ranade, N., Danyko, C., Gegenhuber, B., Fischer, S., Robinson, B.D., Lepor, H., Tollkuhn, J., Gillis, J., Brouzes, E., Krasnitz, A., Levy, D. and Wigler, M. | 2019 | Copolymerization of single-cell nucleic acids into balls of acrylamide gel. Genome Research, 30: 49-61. | ||
| + | |~~=row()~~.| Moffitt, A.B., Spector., M.S., Andrews, P., Kendall, J., Alexander, J., Stepansky, A., Ma, B.C., Kolitz, J., Chiorazzi, N., Allen, S.L., Krasnitz, A., Wigler, M., Levy, D. and Wang, Z. | 2020 | Multiplex accurate sensitive quantitation (MASQ) with application to minimal residual disease in acute myeloid leukemia. | ||
| + | |~~=row()~~.| Chorbadjiev, | ||
| + | |~~=row()~~.| Baslan, T., Kendall, J., Volyanskyy, K., McNamara, K., Cox, H., D’Italia, S., Ambrosio, F., Riggs, M., Rodgers, L., Leotta, A., Song, J., Mao, Y., Wu, J., Shah, R., Merida, R.G., Chadalavada, | ||
| + | |~~=row()~~.| Vasudevan, A., Baruah, P.S., Smith, J.C., Wang, Z., Sayles, N.M., Andrews, P., Kendall, J., Leu, J., Chunduri, N.K., Levy, D., Wigler, M., Storchová, Z., Sheltzer, J.M. |2020| Single-Chromosomal Gains Can Function as Metastasis Suppressors and Promoters in Colon Cancer. Dev Cell. 4: 413-428.e6. | {{: | ||
| + | |~~=row()~~.| Miyabayashi, | ||
| + | |~~=row()~~.| Yoon S, Munoz A, Yamrom B, Lee Y-h, Andrews P, Marks S, Wang Z, Reeves C, Winterkorn L, Krieger AM, Buja, A, Pradhan K. Ronemus M, Baldwin KK, Levy D, Wigler M, Iossifov I. |2021| Rates of contributory de novo mutation in high and low risk autism families. Nature Communications Biology, 4: 1026. PMCID: | ||
| + | |~~=row()~~.| Li S, Park S, Ye C, Danyko C, Wroten M, Andrews P, Wigler M, and Levy D. |2022| Targeted de novo phasing and long-range assembly by template mutagenesis. | ||
| + | |~~=row()~~.| Wang Z, Moffitt A, Andrews P, Wigler M, Levy D. |2022| Accurate measurement of microsatellite length by disrupting its tandem repeat structure. | ||
| + | |~~=row()~~.| Wroten M, Yoon S, Andrews P, Yamrom B, Ronemus M, Buja A, Krieger AM, Levy D, Ye K, Wigler M, and Iossifov I. |2023| Sharing parental genomes by siblings concordant or discordant for autism. Cell Genomics 3: 100319. PMCID: PMC10300587 | {{: | ||
| + | |~~=row()~~.| Li S, Alexander J, Kendall J, Andrews P, Rose E, Orjuela H, Park S, Podszus C, Shanley L, Ma R, Rishi A, Donoho DL, Goldberg GL, Levy D, and Wigler M. |2023| High-throughput single-nucleus hybrid sequencing reveals genome-transcriptome correlations in cancer. | ||
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